Next-generation sequencing applications, such as ChIP-Seq, RNA-Seq, RIP-Seq, exome sequencing, and whole genome sequencing require precise sample fragmentation (200-600 bp) for compatibility with short read sequencing platforms. Shearing by physical sonication, as opposed to enzymatic methods, is preferred for its unbiased nature and ability to produce a relatively narrow fragmentation profile.

However, most currently available sonication systems are incompatible with high-throughput sample processing or require expensive proprietary plates or tubes. PIXUL is the first and only multi-sample sonicator that delivers extremely consistent shearing of up to 96 samples processed in parallel and is fast, simple, and inexpensive to operate.

https://www.activemotif.com/catalog/1300/pixul-multi-sample-sonicator

Features

PIXUL Multi-Sample Sonicator Highlights

• Consistent: Process 1-96 samples simultaneously with extremely high reproducibility.
• Simple: Fast setup, short learning curve, and easy operation with intuitive touchscreen.
• Fast: Arrayed transducers and no degassing required saves time.
• Flexible: Use up to 12 different sonication conditions per run in 96-well plates for simultaneous processing of DNA, RNA, and protein sample types.
• Affordable: No requirement for buying accessories or expensive proprietary plates or tubes.